Speaker: Dr. Thang Pham (OncoProteomics Lab, Cancer Center Amsterdam, dept. Medical Oncology, Amsterdam UMC)
Title: Artificial intelligence in cancer and proteomics research
Artificial intelligence is playing an increasingly important role in cancer research. Advancement in acquisition technologies has led to largescale data production of various molecular readouts. Coupled with smart learning algorithms, this brings exciting challenges and opportunities for early detection, diagnostic, treatment selection and monitoring of cancers. We apply machine learning techniques in the overlapping fields of bioinformatics, statistical data analysis and mass spectrometry-based proteomics in cancer research. In this talk, I will present various challenges we have come across in data preprocessing, feature selection and incorporation of domain knowledge. I will also present our recent work applying a transformer deep learning architecture for prediction of retention time in liquid chromatography mass spectrometry-based proteomics.